What is aspirin?
Aspirin is a nonsteroidal anti-inflammatory drug (NSAID). It was the first of this class of drug to be discovered.
It contains salicylate, a compound found in plants such as the willow tree and myrtle. Its use was first recorded around 4,000 years agoTrusted Source.
Hippocrates used willow bark for relieving pain and fevers, and some people still use willow bark as a natural remedy for headaches and minor pain.
NSAIDs are a class of drug with the following effects:
- relieving pain
- reducing fever
- lowering inflammation, in higher doses
These drugs are not steroids. Steroids often have similar benefits to NSAIDs, but they are not appropriate for everyone and can have unwanted side effects.
As analgesics, NSAIDs tend to be non-narcotic. This means that they do not cause insensibility or a stupor.
It’s a trademark owned by the German pharmaceutical company Bayer. The generic term for aspirin is acetylsalicylic acid.
It has many uses, including relieving pain and swelling, managing various conditions, and reducing the risk of cardiovascular events in people with a high risk.
Below, we describe these uses in more details.
Pain and swelling Of Aspirin
It can relieve mild to moderate pain, swelling, or both associated with many health issues, such as:
- a cold or flu
- sprains and strains
- menstrual cramps
- long-term conditions, such as arthritis and migraine
For severe pain, a doctor may recommend using aspirin alongside another drug, such as an opioid pain reliever or another NSAID.
Preventing cardiovascular events
The daily use of low-dose aspirin can lower the risk of cardiovascular events in some people — it is not safe for everyone. The Food and Drug Administration (FDA)Trusted Source recommend only using aspirin in this way under the supervision of a doctor.
In people with a high risk of cardiovascular events, low-dose can reduce the risk by preventing blood clots from forming.
A doctor may recommend daily low-dose for people who :
- have a heart or blood vessel disease
- have evidence of poor blood flow to the brain
- have high blood cholesterol
- have high blood pressure, or hypertension
- have diabetes
However, for people without these issues, the risks of long-term aspirin use can outweigh the benefits.
The 2016 recommendations from the United States Preventive Services Task Force say that adults aged 50–59 may take aspirin daily to prevent colorectal cancer, as well as cardiovascular disease. However, this guidance only applies to adults in the age range who:
- have at least a 10% 10-year risk of cardiovascular disease
- do not have a high risk of bleeding
- have a life expectancy of at least 10 years
- are willing to take a daily low dose for at least 10 years
Treating coronary events
Doctors may administer aspirin immediately after a heart attack, stroke, or another cardiovascular event to prevent further clot formation and cardiac tissue death.
It can also be part of a treatment plan for people who have recently had:
- revascularization surgery, such as an angioplasty or coronary bypass surgery
- a mini-stroke, or transient ischemic attack
- an ischemic stroke, which is caused by a blood clot
It can also help treat pain and swelling associated with the following chronic health conditions:
- rheumatic conditions, including rheumatoid arthritis, osteoarthritis, and other inflammatory joint conditions
- systemic lupus erythematosus
- inflammation around the heart, known as pericarditis
Doctors may recommend low-dose aspirin to people:
- with retinal damage, also called retinopathy
- who have had diabetes for more than 10 years
- who are taking antihypertensive medications
- with a risk of colorectal cancer
Doctors do not usually recommend aspirin for people under 18.
This is because it can increase the risk of a serious condition called Reye’s syndrome, which can appear after a viral infection such as a cold, the flu, or chickenpox. Reye’s syndrome can lead to permanent brain injury or death.
However, a clinician may prescribe aspirin to a child under supervision if they have Kawasaki disease or to prevent blood clots from forming after heart surgery.
For children, doctors usually recommend acetaminophen (Tylenol) or ibuprofen (Advil), in appropriate doses, instead of aspirin.
People with the following conditions should be cautious about taking aspirin, and should only do so if a doctor recommends it:
- bleeding disorders, such as hemophilia
- uncontrolled high blood pressure
- peptic or stomach ulcers
- liver or kidney disease
Under a doctor’s supervision, people who are pregnant or breastfeeding may take low-dose aspirin. Doctors usually do not recommend high-dose aspirin during pregnancy.
Anyone with a known allergy to aspirin or any other NSAID, such as ibuprofen, should avoid these drugs.
Doctors do not administer aspirin during a stroke because not all strokes are caused by blood clots. In some cases, aspirin could make a stroke worse.
Also, anyone who drinks alcohol regularly or is undergoing dental or surgical treatment, however small, should ask a doctor before taking aspirin.